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What is Living Evidence?

Living Evidence uses rapid response pathways to incorporate new, relevant evidence into clinical practice.

Living Guidelines can therefore be:

  • underpinned by continual, active evidence surveillance and monitoring.
  • able to rapidly incorporate new, important evidence as it is identified.
  • equipped to communicate the current status of the guideline and any new evidence being incorporated.
  • actively engaged with large and diverse groups of stakeholders.
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Our approach to recommendation development

ALEC uses the world-leading Living Evidence model, combining rigorous, evidence-based methods and rapid updating. This enables us to create and modify recommendations swiftly in response to important new research evidence.

ALEC’s living guidelines use GRADE methods and are designed to meet Australian NHMRC standards.

Guideline Development Process

> Relevant new questions to be addressed are sought from stakeholders and practitioners.

> For prioritised questions, the evidence is actively monitored and updated. An evidence team appraises and synthesises evidence and prepares evidence-to-decision frameworks to inform development of recommendations by multidisciplinary clinical panels.

> A Guideline Leadership Group oversees the development of recommendations.

> The evidence team, clinical panels and Guideline Leadership Group are advised by a Lived Experience Panel.

> After initial agreement by the Guideline Leadership Group, all recommendations then require 100% consensus by a Steering Committee comprised of member organisations.

> Endorsed recommendations are published online and disseminated through traditional and social media channels.

> The process begins again.

Return on investment

Our National Clinical Evidence Taskforce was responsible for the successful development of living guidelines during the COVID-19 pandemic. We supported health professionals throughout the pandemic by providing up to date, highly valued guidance during a time of significant misinformation. Using the Living Evidence model, the Guidelines were able to be updated weekly and were based on daily evidence surveillance.

Modelling of the impact of the COVID-19 living guidelines suggests that they prevented at least 12,257 COVID-19 hospitalisations and 545 COVID-19 deaths.

The return on investment was $139.86, meaning an approximate $140 return for every $1 invested. Read the published paper here.

 

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How we developed
living guidelines
throughout the
COVID-19 pandemic
National Clinical Evidence Taskforce logo
The Taskforce explainer infographic cannot be viewed on mobile.
Please come back and experience on tablet or larger.
Questions needed answers
We established a
multi-disciplinary collaboration
between researchers and clinicians
to provide evidence-based,
trustworthy guidance for the
treatment of people with COVID-19.
Join the dots as we step
through the process
Blue signifies the work of the Evidence Team
Pink signifies the
contributions
of the Expert
Panels and Groups

Evidence in action

Partners
and funders